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Excerpt from:  Fountain of Youth Project
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October 13, 2005

How much fruit...is a good thing, or a bad thing?

Well, it depends...in some people, fruit raises blood lipid levels (triglycerides) decreasing health...you may need to limit fructose intake.

One of the key ingredients of our Fountain of Youth Project and working with you, my transforming man, is to limit disease progression and reverse some conditions through healthy means. This includes diet modification and exercise rather than the use of prescription medications.

Unlike meds, healthy foods have few inherent side effects when eaten in moderation. However, in certain people - and those with metabolic "defects" - even healthy foods can create problems.

Many people have become aware of the ill effects of dietary saturated fat and its ability to stimulate endogenous (within your body) cholesterol production leading to hypercholesterolemia (high blood cholesterol levels). Saturated fats, along with hydrogenated oils (trans fatty acids), stimulate the Mevolonate pathway in the liver to increase the body's production of cholesterol; leading to higher blood levels. Often this can be treated with diet modification rather than Rx meds. Hence, my recent recommendation for you is to increase your supplemental fiber (using both Psylium Husk - water insoluble fiber, and Methylcellulose - water soluble fiber), along with your dietary fiber intake, to take in a total of 40 grams or more per day.

On the flip side of saturated and trans fats which are primarily unhealthy, fruits are generally considered to be extremely healthy. This is true except in certain individuals who hereditarily are predisposed to hypercholesterolemia and hypertriglyceridemia. Once their high cholesterol levels are reduced and controlled - particularly through medication but also through diet, exercise, and lifestyle modifications - blood triglyceride levels begin to rise or remain high.

I first learned about the link between fruit and hypertriglyceridemia while at UCLA during my doctoral research program. My graduate advisor, R. James Barnard, Ph.D. was the Chief Researcher for the Pritikin Longevity Center. Among the many other critical and extremely useful items I learned from him was the role of fruit in elevating blood lipid levels in certain people. In research performed on those in the Center, a certain segment of the participants in the month long, in-house disease regression program were unable to lower their blood triglyceride level while on the typical regression diet. It wasn't until fruit intake was limited that blood triglyceride levels dropped alongside blood cholesterol levels.

And that is why we are testing no fruit on you, Mr. Transformer. Apparently you may be one of those unlucky few whose liver, which normally metabolizes fructose and turns it preferentially into glucose, turns it into fat.

Two weeks ago your blood triglyceride levels fluctuated somewhere around 500 mg/dl. In another week we will see how this experiment works when you go in for your next blood test. If, as I suspect, your elevated blood triglyceride levels are mostly due to your metabolism's inability to normally utilize fructose then we will limit your intake of foods which contain fructose or high-fructose corn syrup. You already eat a diet low in  saturated fat and total fat and high in fiber. If it is the case that your elevated triglyceride levels are due to your high fructose intake then we will celebrate our latest discovery by slowly reintroducing fruit back into your diet in limited amounts.


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